Laparoscopic Heller's Myotomy for Achalasia Cardia: An Outcome and Experience of a Single-Center Study

المؤلفون

  • Noori Hanoon Jasim Basrah Gastroenterology and Hepatology Teaching Hospital, College of Medicine, University of Basrah, Basrah Iraq https://orcid.org/0000-0001-9178-061X
  • Muntadher Abdulkareem Abdullah Basrah Gastroenterology and Hepatology Teaching Hospital, College of Medicine, University of Basrah, Basrah Iraq https://orcid.org/0000-0002-8893-1920
  • Khalid Shaker Abdulkarim Basrah Gastroenterology and Hepatology Hospital, Basrah Health Directorate, Basrah, Iraq
  • Ali Dawood Al-hilfi Basrah Gastroenterology and Hepatology Hospital, Basrah Health Directorate, Basrah, Iraq

DOI:

https://doi.org/10.54133/ajms.v10i2.2949

الكلمات المفتاحية:

Achalasia cardia، Dysphagia، Fundoplication، Hiller myotomy ، Manometry

الملخص

Background: Achalasia cardia is a rare disease mostly caused by myenteric plexus degeneration. The main clinical presentations are dysphagia, regurgitation, chest pain, and weight loss. Objectives: This study aimed to evaluate the feasibility and outcome of laparoscopic Heller's myotomy. Methods: This is a prospective study involving 52 patients with achalasia diagnosed by OGD, barium swallow, and esophageal manometry. All patients underwent laparoscopic surgery. Results: This study includes 23 males and 29 females with a male/female ratio of 1.26. The mean age of patients was 36.8 years. The mean operative time was 85.12 minutes, with a mean hospital stay of 4.27 days. All patients had undergone laparoscopic Heller's myotomy with Dor fundoplication; there were no conversions to open surgery. Intraoperatively detected complications involve 4 patients with esophageal mucosal injury, 1 patient with gastric mucosal injury, and 2 patients with minute pleural injury and no significant intraoperative bleeding, adjacent organ injury, or surgical emphysema. Regarding the early postoperative complications, 3 patients (5.76%) had atelectasis, 1 patient (1.92%) had pneumonia, and 1 patient (1.92%) had a leak due to a missed esophageal mucosal injury discovered on the third postoperative day; 3 patients (5.88%) with mild dysphagia were successfully treated conservatively, and one patient (1.92%) died on the sixth postoperative day. About late complications, 4 patients (7.84%) developed mild GERD, and 1 patient developed recurrent dysphagia. Conclusions: Laparoscopic Heller's myotomy is feasible and effective therapy for achalasia cardia. DOR fundoplication is a competent anti-reflux procedure to decrease the rate of postoperative GERD.

التنزيلات

بيانات التنزيل غير متوفرة بعد.

المراجع

Mirsharifi A, Ghorbani AA, Mirsharifi R, Jafari M, Fattah N, Mikaeli J, et al. Laparoscopic Heller myotomy for achalasia: experience from a single referral tertiary center. Middle East J Dig Dis. 2019;11(2):90-97. doi: 10.15171/mejdd.2018.133. DOI: https://doi.org/10.15171/mejdd.2018.133

Boeckxstaens G E, Zaninotto G, Richter JE. Achalasia. Lancet. 2014;383(99911):83-93. doi: 10.1016/S0140-6736(13)60651-0. DOI: https://doi.org/10.1016/S0140-6736(13)60651-0

Li MY, Wang QH, Chen RP, Su XF, Wang DY. Pathogenesis, clinical manifestations, diagnosis, and treatment progress of achalasia of cardia. World J Clin Cases. 2023;11(8):1741-1752. doi: 10.12998/wjcc. v11.i8.1741. DOI: https://doi.org/10.12998/wjcc.v11.i8.1741

Swanström LL. Achalasia: treatment, current status and future advances. Korean J Intern Med. 2019;34(6):1173-1180. doi: 10.3904/kjim.2018.439. DOI: https://doi.org/10.3904/kjim.2018.439

Riccio F, Costantini M, Salvador R. Esophageal achalasia: diagnostic evaluation. World J Surg. 2022;46(7):1516–1521. doi: 10.1007/s00268-022-06483-3. DOI: https://doi.org/10.1007/s00268-022-06483-3

Slim N, Williamson JM. Achalasia: Investigation and management. Br J Hosp Med (Lond). 2023;84(1):1-9. doi: 10.12968/hmed.2022.0437. DOI: https://doi.org/10.12968/hmed.2022.0437

Agrawal PP, Joshi AS. Laparoscopic Heller’s cardiomyotomy for achalasia cardia-a case series with review of literature. Int Surg J. 2024;11(2):238-224. doi: 10.18203/2349-2902.isj20240176. DOI: https://doi.org/10.18203/2349-2902.isj20240176

Katada N, Sakuramoto S, Yamashita K, Shibata T, Moriya H, Kikuchi S, et al. Recent trends in the management of achalasia. Ann Thorac Cardiovasc Surg. 2012;18(5):420–428. doi: 10.5761/atcs.ra.12.01949. DOI: https://doi.org/10.5761/atcs.ra.12.01949

Mustian M, Wong K. Surgical management of achalasia. Abdom Radiol. 2025;50(6):2351–2357. doi: 10.1007/s00261-024-04664-3. DOI: https://doi.org/10.1007/s00261-024-04664-3

Abir F, Modlin I, Kidd M, Bell R. Surgical treatment of achalasia: current status and controversies. Dig Surg. 2004;21(3):165-176. doi: 10.1159/000079341. DOI: https://doi.org/10.1159/000079341

Familiari P, Greco S, Volkanovska A, Gigante G, Cali A, Boškoski I, et al. Achalasia: current treatment options. Expert Rev Gastroenterol Hepatol. 2015;9(8):1101–1114. doi: 10.1586/17474124.2015.1052407. DOI: https://doi.org/10.1586/17474124.2015.1052407

Arber N, Grossman A, Lurie B, Hoffman M, Rubinstein A, Lilos P, et al. Epidemiology of achalasia in central Israel. Rarity of esophageal cancer. Dig Dis Sci. 1993;38(10):1920-1925. doi: 10.1007/BF01296119. DOI: https://doi.org/10.1007/BF01296119

Kaman L, Iqbal J, Kochhar R, Sinha S. Laparoscopic heller myotomy for achalasia cardia-initial experience in a teaching institute. Indian J Surg. 2013;75(5):391-394. doi: 10.1007/s12262-012-0708-0. DOI: https://doi.org/10.1007/s12262-012-0708-0

Pomenti S, Blackett JW, Jodorkovsky D. Achalasia: diagnosis, management and surveillance. Gastroenterol Clin North Am. 2021;50(4):721-736. doi: 10.1016/j.gtc.2021.07.001. DOI: https://doi.org/10.1016/j.gtc.2021.07.001

Sato H, Takahashi K, Mizuno KI, Hashimoto S, Yokoyama J, Terai S. A clinical study of peroral endoscopic myotomy reveals that impaired lower esophageal sphincter relaxation in achalasia is not only defined by high-resolution manometry. PLoS One. 2018;13(4): e0195423. doi: 10.1371/journal.pone.0195423. DOI: https://doi.org/10.1371/journal.pone.0195423

Licurse MY, Levine MS, Torigian DA, Barbosa EM. Utility of chest CT for differentiating primary and secondary achalasia. Clin Radiol. 2014;69(10):1019-1026. doi: 10.1016/j.crad.2014.05.005. DOI: https://doi.org/10.1016/j.crad.2014.05.005

Kahrilas PJ, Bredenoord AJ, Fox M, Gyawali CP, Roman S, Smout AJ, et al. International high resolution manometry working group. The Chicago Classification of esophageal motility disorders, v3.0. Neurogastroenterol Motil. 2015;27(2):160-174. doi: 10.1111/nmo.12477. DOI: https://doi.org/10.1111/nmo.12477

Ghoshal UC, Das Chakraborty SB, Singh R. Pathogenesis of achalasia cardia. World J Gastroenterol. 2012;18(24):3050-3057. doi: 10.3748/wjg.v18.i24.3050. DOI: https://doi.org/10.3748/wjg.v18.i24.3050

Perrone JM, Frisella MM, Desai KM, Soper NJ. Results of laparoscopic Heller-Toupet operation for achalasia. Surg Endosc. 2004;18(11):1565-571. doi: 10.1007/s00464-004-8912-z. DOI: https://doi.org/10.1007/BF02637121

Chadalavada P, Thota PN, Raja S, Sanaka MR. Peroral endoscopic myotomy as a novel treatment for Achalasia: Patient selection and perspectives. Clin Exp Gastroenterol. 2020;13:485-495. doi: 10.2147/CEG.S230436. DOI: https://doi.org/10.2147/CEG.S230436

Ramchandani M, Pa P. Achalasia Cardia: A Comprehensive review. EMJ Gastroenterol. 2020;9(1):106-117. doi: 10.33590/emjgastroenterol/20-00178. DOI: https://doi.org/10.33590/emjgastroenterol/20-00178

Kumar HR. The current surgical management of achalasia cardia: review article. SAR J Surg. 2025;6(5):113-118. doi: 10.36346/sarjs.2025.v06i05.004. DOI: https://doi.org/10.36346/sarjs.2025.v06i05.004

Patti MG, Pellegrini CA, Horgan S, Arcerito M, Omelanczuk P, Tamburini A, et al. Minimally invasive surgery for achalasia: an 8-year experience with 168 patients. Ann Surg. 1999;230(4):587-593;593-594. doi: 10.1097/00000658-199910000-00014. DOI: https://doi.org/10.1097/00000658-199910000-00014

Gülpınar K, Celasin H, Sözener U, Türkcapar A. The therapeutic results after laparoscopic Heller's myotomy and partial fundoplication for achalasia. Turk J Gastroenterol. 2014;25(Suppl 1):54-58. doi: 10.5152/tjg.2014.4944. DOI: https://doi.org/10.5152/tjg.2014.4944

التنزيلات

منشور

2026-05-15

كيفية الاقتباس

Jasim, N. H., Abdullah, M. A., Abdulkarim, K. S., & Al-hilfi, A. D. (2026). Laparoscopic Heller’s Myotomy for Achalasia Cardia: An Outcome and Experience of a Single-Center Study. Al-Rafidain Journal of Medical Sciences, 10(2), 242–247. https://doi.org/10.54133/ajms.v10i2.2949

إصدار

القسم

Original article